Hansuke Yamamoto was born in Chiba, Japan and started ballet at the age of 13 under the tutelage of Akira Egawa. He entered the Royal Ballet School in 1996 and graduated at the top of the class in 1998. Subsequently, Yamamoto studied under Hiroaki Imamura and Yuriko Kawaguchi at Ballet Chambre Ouest. From 1999 to 2001, he was a member of the National Ballet of Canada, after which he joined San Francisco Ballet in 2001 and was promoted to soloist in 2005. In 2011, he received the Isadora Duncan Dance Award for the lead role in Classical Symphony in the Performance Ensemble category. Yamamoto retired from San Francisco Ballet in 2023.

Yamamoto performed as a soloist and lead in many works by world-renowned choreographers such as Helgi Tomasson, Jerome Robbins, Sir Frederick Ashton, George Balanchine, Sir Kenneth MacMillan, John Neumeier, David Bintley, Hans van Manen, Mark Morris, Yuri Possokhov, Alexei Ratmansky, Liam Scarlett, Justin Peck, James Kudelka, Stanton Welch, Christopher Wheeldon, Caniparoli, Forkin, Harald Lander, Serge Lifar, Cathy Marston, Rudolf Nureyev, Arthur Pita, Myles Thatcher, and Renato Zanella. During his 22-year tenure at San Francisco Ballet, he danced nearly 100 repertoire pieces. In July 2023, he was appointed head of the boys’ program at EleNobele – The Finest Ballet Training Program, based in Tokyo. Hansuke joined San Francisco Ballet School as a member of the faculty in 2024.